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DeCS
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Descriptor English:
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Porphyria, Variegate
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Descriptor Spanish:
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Porfiria Variegata
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Descriptor Portuguese:
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Porfiria Variegada
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Synonyms English:
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Porphyria Variegata
Porphyria Variegate
Ppox Deficiency
Protoporphyrinogen Oxidase Deficiency
Variegate Porphyria
Deficiencies, Protoporphyrinogen Oxidase
Porphyria Variegates
Variegate, Porphyria
Variegates, Porphyria
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Tree Number:
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C06.552.830.625
C16.320.850.742.625
C17.800.827.742.625
C18.452.811.400.625
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Definition English:
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An autosomal dominant porphyria that is due to a deficiency of protoporphyrinogen oxidase (EC 1.3.3.4) in the LIVER, the seventh enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features include both neurological symptoms and cutaneous lesions. Patients excrete increased levels of porphyrin precursors, COPROPORPHYRINS and protoporphyrinogen. |
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History Note English:
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2005; use PORPHYRIA, HEPATIC 1993-2004
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Allowable Qualifiers English:
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Record Number:
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38625
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Unique Identifier:
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D046350
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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